PAIA Biotech

PAIA Biotech has developed a platform technology for the analysis and quantification of antibodies and proteins in high throughput.

PAIA Biotech has developed a platform technology for the analysis and quantification of antibodies and proteins in high throughput. The PAIA technology streamlines bead-based assays by eliminating several assay steps with specially designed PAIA microplates. This leads to significantly reduced hands-on time and a fully automatable workflow. They offer assay kits comprising PAIA plates and a combination of functionalized capture beads and a fluorescence marker which is optimized for a given application. Their current focus is to provide a portfolio of assays kits for the quantification of antibodies and antibodies derived molecules like antibody fragments and Fc-fusions proteins. With this set of assays they cover the typical concentrations ranges of antibodies in the different stages of cell line and bioprocess development. They aim at providing reliable and easy-to-use solutions to quantify IgG in hundreds to thousands of samples per day without the need to purchase a dedicated instrument and without sensors that need to be regenerated. PAIA assays are performed on common orbital shakers for incubation and read out on standard fluorescence readers or microscopes. They exclusively use fluorescence detection in the far red wavelength range to avoid matrix effects from complex cell culture supernatants.